Research Teams
FHU FRAME relies on a network of research teams recognized at both national and international levels in the fields of reproductive pathophysiology, immunology, genomics, microbiome research, imaging, and social and human sciences.
These teams contribute to a multidisciplinary approach to endometriosis and adenomyosis by combining basic research, translational research, and clinical research. This organization makes it possible to better understand the biological mechanisms underlying the disease and to foster the development of new diagnostic and therapeutic strategies.
Institut Cochin – INSERM U1016
The Institut Cochin is one of the main biomedical research centers involved in FHU FRAME.
Two research teams from the INSERM U1016 unit actively contribute to the consortium’s projects.
Pathogenesis and Innovative Treatments of Chronic Fibro-Inflammatory Diseases
Head: Pr Frédéric Batteux
Endometriosis Chair: Dr Ludivine Doridot
This team studies the cellular and molecular mechanisms involved in chronic inflammatory diseases. Within the framework of FHU FRAME, their work focuses particularly on the identification of diagnostic and prognostic biomarkers for endometriosis, as well as on the development of new therapeutic approaches.
From Gametes to Birth: Genomics, Epigenetics and Physiology of Reproduction
Head: Dr Daniel Vaiman
This team investigates the genetic and epigenetic mechanisms involved in human reproduction and embryonic development. Their research contributes in particular to understanding the impact of endometriosis and assisted reproductive technologies on embryonic development.
Institut Necker Enfants Malades – INSERM U1151
Head: Pr Guillaume Canaud
The INSERM U1151 unit develops innovative approaches in genomic medicine and cellular biology in order to improve the understanding of complex diseases. Research conducted within the framework of the FHU contributes to the identification of molecular mechanisms involved in endometriosis and to the exploration of new therapeutic targets.
The integration of these research teams enables FHU FRAME to cover the full spectrum of scientific dimensions related to endometriosis and adenomyosis, from molecular mechanisms to the societal implications of the disease.
This close collaboration between researchers, clinicians, and specialists from multiple disciplines represents a key driver for advancing knowledge and improving patient care.