Translational Research Units
FHU FRAME relies on several structures dedicated to clinical and translational research, which play a crucial role in transforming scientific discoveries into diagnostic and therapeutic innovations for patients with endometriosis and adenomyosis.
These infrastructures facilitate the coordination of clinical studies, ensure the methodological and regulatory quality of research projects, and promote the integration of clinical, biological, and imaging data.
Clinical Investigation Center (CIC) Cochin – Necker
The Clinical Investigation Center (CIC) Cochin–Necker is a key structure for the development and implementation of clinical studies conducted within FHU FRAME.
The CIC supports medical and scientific teams throughout all stages of clinical research projects, including:
- Study design and methodology
- Implementation of clinical protocols
- Patient recruitment and follow-up
- Coordination of multicenter studies
- Clinical data management and quality control
Through its expertise, the CIC helps ensure the scientific rigor and regulatory compliance of research projects.
Clinical Research Unit (URC) Cochin – Necker
The Clinical Research Unit (URC) Cochin–Necker provides methodological and operational support to teams involved in clinical research projects.
Its activities include:
- Development and structuring of research projects
- Preparation of regulatory submissions
- Management of funding applications and research calls
- Coordination of clinical trials
- Statistical analysis and data exploitation
The URC therefore plays a central role in the development and coordination of clinical studies supported by FHU FRAME.
Imaging and Data Analysis Platforms
FHU FRAME projects also rely on imaging and data analysis platforms aimed at improving the characterization of endometriosis lesions and developing new diagnostic tools.
These infrastructures contribute in particular to:
- Standardization of imaging protocols
- Advanced analysis of medical images
- Development of decision-support tools for diagnosis and surgical planning
Clinical Cohorts and Databases
FHU FRAME also relies on clinical and radiological databases enabling the development of patient cohorts followed in the expert centers of the consortium.
These databases allow researchers to:
- Analyze the evolution of the disease
- Identify prognostic factors
- Evaluate therapeutic strategies
- Develop clinical decision-support tools
A Direct Link Between Basic and Clinical Research
Translational research units are a central component of the organization of FHU FRAME. They connect basic research teams, hospital teams, and technological infrastructures in order to foster the emergence of innovative projects.
This structure promotes an integrated research dynamic, accelerating the production of scientific knowledge and its transfer into clinical practice for the benefit of patients.